- combinatorial libraries
- Макаров: комбинаторные библиотеки
Универсальный англо-русский словарь. Академик.ру. 2011.
combinatorial libraries
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Combinatorial chemistry — involves the rapid synthesis or the computer simulation of a large number of different but structurally related molecules or materials. It is especially common in CADD (Computer aided drug design) and can be done online with web based software,… … Wikipedia
Combinatorial biology — This article is about the generation and assessment of biomedical compounds. For combinatorial phylogenetic modeling, see Mathematical biology. Comparison of natural and synthetic selection processes for peptide generation. In biotechnology,… … Wikipedia
Dynamic combinatorial chemistry — is defined as combinatorial chemistry under thermodynamic control.[1] Contents 1 Introduction 2 Current Applications 2.1 Medicine and Pharmaceutical … Wikipedia
DNA-encoded chemical library — DNA encoded chemical libraries (DEL) are a new technology for the synthesis and screening of collections of chemical compounds of unprecedented size and quality. DEL represents an advance in medicinal chemistry which bridges the fields of… … Wikipedia
Richard A. Houghten — is a molecular biologist and founder of the journal Peptide Research , which was later merged with the International Journal of Peptide and Protein Research, to become the Journal of Peptide Research . His work mainly concerns peptide activity… … Wikipedia
Morten P. Meldal — (born 1954 in Denmark) is a Danish chemist. He is presently serving as a professor of Chemistry at University of Copenhagen in Copenhagen, Denmark. He is best known for developing the CuACC click reaction[1][2] and polyethylene glycol (PEG) resin … Wikipedia
Kim Janda — Kim D. Janda (born 23 August, 1957) is an American chemist who studies on medicinal chemistry, molecular biology, immunology and neuropharmacology.Janda currently holds the rank of the Ely R. Callaway, Jr. Chaired Professor in the Departments of… … Wikipedia
Daptomycin — Systematic (IUPAC) name N decanoyl L tryptophyl L asparaginyl L aspartyl L threonylglycyl L ornithyl L aspartyl D alanyl L aspartylglycyl D seryl threo 3 methyl L glutamyl 3 anthraniloyl L alanine[egr]1 lactone … Wikipedia
Drug discovery hit to lead — Early drug discovery involves several phases from target identification to preclinical development. The identification of small molecule modulators of protein function and the process of transforming these into high content lead series are key… … Wikipedia
DARPins — Strukturmodell eines DARPins basierend auf Röntgenstrukturanalysedaten (PDB 2QYJ) DARPins (kurz von engl. Designed Ankyrin Repeat Proteins) sind künstliche Proteine, die zur Erkennung und Bindung von Antigenen befähigt sind. Sie sind strukturell… … Deutsch Wikipedia
DARPin — A DARPin with four ankyrin repeat motifs (PDB 1N0R) DARPins (an acronym for designed ankyrin repeat proteins) are genetically engineered antibody mimetic proteins typically exhibiting highly specific and high affinity target protein binding. They … Wikipedia
